In vitro analysis of the Singing Arrow Oxyphone Delivery System and VixOne Disposable Nebulizer with Unit Dose Albuterol (2.5mg/3ml)
It was somewhat of a surprise that Oxyphone, with the mouthpiece about 4 cm from the mouth of the model, exceeded the performance of a close-fitting mask . (Presented at American Thoracic Society meeting in Toronto, May 2008)
n = 5
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OxyphoneÔ
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AFM 1
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AFM @ 2 2
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VMD
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4.3 ± 0.1 mm
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GSD
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2.0
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% £ 3mm
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37% ± 0.8
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% £ 5mm
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57% ± 1.2
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Duration
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6.0
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Residual Dose (mg)
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1.34 ± 0.13
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1.58 ± 0.13
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1.32 ± 0.03
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Inhaled Dose (mg)
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0.337 ± 0.05
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0.205 ± 0.01
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0.097 ± 0.04
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Fine Particle Dose (mg)
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0.191 ± 0.03
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0.116 ± 0.01
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0.055 ± 0.02
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Output (FPD/Min)
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0.03 ± 0.0
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0.02 ± 0.0
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0.01 ± 0.0
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FPD %
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7.6 % ± 1.2
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4.6 % ± 0.3
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2.2 % ± 0.9
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mean ± sd
1. AFM: Aerosol Face Mask
2. AFM@2: Aerosol Face Mask 2 cm from face
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